a-c, The N501Y variant was mixed with wt virus and inoculated intranasally into hamsters. The replication kinetics of the mixed viruses in the nasal washes (a), ...
Nov 24, 2021 · Our results suggest that N501Y is a critical determinant of enhanced infection of the upper airway and transmission.
Mutations in the spike protein can change the virus' fitness, increasing its affinity for target cells, its transmissibility and its virulence.
RBD with the N501Y mutation exhibited a considerably stronger interaction, with a faster association rate and a slower dissociation rate.
Dec 24, 2020 · 新變種病毒與此前在英國發現的變種病毒具有一些相似之處，儘管它們是分開發展的。 兩者都有叫做「N501Y」的突變，它是病毒用來感染人體細胞的關鍵部分。
Apr 24, 2021 · 由於該宗源頭不明個案涉及N501Y變種病毒株，為阻截N501Y變種病毒株擴散的潛在風險，中心採取了審慎的感染控制措施，昨晚就病人居住的大廈（半山堅 ...
Aug 19, 2021 · Several SARS-CoV-2 lineages with spike receptor binding domain (RBD) N501Y mutation have spread globally. We evaluated the impact of N501Y ...
Apr 23, 2021 · 南非变种病毒于2020年12月31日已抵港，患者从南非经多哈抵港，但彼时并未流入香港社区，香港政府在机场将确诊人士截流。 南非变种病毒（B.1.351）约在去年10月 ...
2021年5月，香港錄得11宗涉及傳染性較高的N501Y變種病毒株個案，當中一名17歲女子 ... 6月尾，另一宗帶有L452R變異基因（個案11902）則屬Delta變種病毒株。 變異 ...
Jul 27, 2021 · The N501Y mutation in the receptor-binding domain (RBD) of S glycoprotein has been found to be the only shared mutation present on the S glycoprotein.