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The Los Angeles Clippers and Los Angeles Lakers rekindle a high-profile rivalry on Thursday. The matchup, set to take place at a shared venue of Crypto.com Arena, is the second of the season between the teams, with the Clippers winning the first game in early December. The Clippers, who are operating as the home team, are 26-27 overall and on full rest, while the Lakers (25-27) are on the second night of a back-to-back set after beating Portland on Thursday. LeBron James (knee) hasn't played since Jan. 25 and is out for this game as well. The Clippers officially list Ivica Zubac (calf) as questionable, while Kawhi Leonard (knee) and Paul George (elbow) remain out. 

Tipoff is at 10 p.m. ET. The Clippers are 3.5-point favorites in the latest Lakers vs. Clippers odds from Caesars Sportsbook. The over-under for total points is set at 220. Before locking in any Clippers vs. Lakers picks, be sure to see the NBA predictions and betting advice from SportsLine's proven computer model. 

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 16 of the 2021-22 NBA season on a stunning 62-32 roll on all top-rated NBA picks, returning over $2,500. Anyone following it has seen huge returns.

Now, the model has set its sights on Lakers vs. Clippers, and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA betting lines and trends for Clippers vs. Lakers:

  • Lakers vs. Clippers spread: Clippers -3.5
  • Lakers vs. Clippers over-under: 220 points
  • Lakers vs. Clippers money line: Clippers -160, Lakers +140
  • LAL: The Lakers are 4-2 against the spread with no rest
  • LAC: The Clippers are 12-15 against the spread in home games

Why the Lakers can cover

The Lakers have strengths on offense, including a top-five mark in fast-break points. Los Angeles is also in the top 10 of the NBA in points in the paint, and the Lakers are above the league average in field-goal percentage, 2-point percentage and free-throw creation. On defense, the Lakers are above-average in preventing 3-pointers, with top-10 marks in turnover creation, steals per game and blocked shots per game. 

This is also a favorable matchup for the Lakers on the defensive end, with the Clippers struggling on offense. The Clippers are No. 26 in the NBA in offensive efficiency, illustrating overall shortcomings, and they are also No. 27 in offensive rebound rate, last in second-chance points and No. 27 in points in the paint. The Clippers are also in the bottom 10 of the NBA in field-goal percentage, 2-point percentage and turnover rate on the offensive side.

Why the Clippers can cover

The Clippers are electric on the defensive end of the floor. They are allowing only 107.5 points per 100 possessions this season, No. 6 in the NBA, and the Clippers are elite at contesting shots. Opponents are shooting 44.2 percent against the Clippers, No. 7 in the NBA, with top-five marks in 3-point percentage allowed (33.1 percent), 2-point percentage allowed (50.9 percent) and free-throw attempts allowed (18.8 per game). 

The Clippers force 14.1 turnovers per game, a top-10 mark, and that includes 7.5 steals per game. Opponents are also averaging only 24 assists per game against the Clippers, and the Lakers are No. 23 in the NBA in offensive efficiency. The Lakers also scuffle significantly in offensive rebound rate (No. 24), second-chance points (No. 28) and turnovers (No. 26), adding to an already favorable defensive projection for the Clippers.

How to make Clippers vs. Lakers picks

SportsLine's model is leaning under on the total, projecting 211 points. The model also says one side of the spread hits 70 percent of the time. You can only see the model's pick at SportsLine.

So who wins Lakers vs. Clippers? And which side of the spread hits 70 percent of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its NBA picks, and find out.